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Solved 2024: FYUG EVEN SEMESTER EXAM, 2024 ZOOLOGY (2nd Semester) Cell Biology and Histology

Course No.: ZOODSM-151T | Full Marks: 70 | Time: 3 Hours

Subject: Zoology (Cell Biology and Histology)

Paper Code: ZOODSM-151T

Exam: FYUG Even Semester Exam, 2024


SECTION-A

Answer any ten of the following questions (All solved for full coverage):

1. Define cell in the light of cell theory. [2]

According to cell theory, a cell is the basic structural, functional, and biological unit of all living organisms

. It is the smallest unit of life that can replicate independently.

2. What do you mean by facilitated transport? [2]

Facilitated transport is a type of passive transport where molecules move across the cell membrane through specific transmembrane integral proteins without the expenditure of cellular energy

.

3. Differentiate between prokaryotic and eukaryotic cell. [2]

4. Mention the functions of lysosome. [2]

  • Intracellular digestion of macromolecules.
  • Autophagy (digestion of old or damaged organelles).
  • Autolysis (self-destruction of the cell).
  • 5. Mention important functions of peroxisome. [2]

  • Breakdown of fatty acids through beta-oxidation.
  • Detoxification of harmful substances (like alcohol) in the liver.
  • Conversion of hydrogen peroxide to water and oxygen by catalase.
  • 6. Why is mitochondria called powerhouse of the cell? [2]

    Mitochondria are called the powerhouse of the cell because they are the primary sites of ATP (Adenosine Triphosphate) production through cellular respiration

    .

    7. What are microtubules? [2]

    Microtubules are hollow, microscopic cylinders made of tubulin protein that form part of the cytoskeleton and play key roles in maintaining cell shape and facilitating cell division

    .

    8. What are nucleosomes? [2]

    A nucleosome is the basic structural unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound around a core of eight histone proteins

    .

    9. Define cell cycle. [2]

    The cell cycle is an ordered series of events involving cell growth and DNA replication that produces two new daughter cells

    .

    10. What is pseudostratified epithelial tissue? [2]

    It is a type of simple epithelium that appears layered (stratified) because the nuclei are at different levels, even though every cell is attached to the basement membrane

    .

    11. Differentiate between tendon and ligament. [2]

  • Tendon: Connects skeletal muscle to bone.
  • Ligament: Connects bone to bone.
  • 12. What is Haversian system? [2]

    The Haversian system (or osteon) is the fundamental functional unit of compact bone, consisting of concentric layers of bone tissue surrounding a central canal containing blood vessels and nerves

    .

    13. Enlist the locations of smooth muscle in human body. [2]

  • Walls of hollow organs (stomach, intestines).
  • Walls of blood vessels.
  • Urinary bladder and respiratory tracts.
  • 14. What are glial cells? [2]

    Glial cells (neuroglia) are non-neuronal cells in the nervous system that provide support, nutrition, and protection for neurons

    .

    15. What is neuromuscular junction? [2]

    A neuromuscular junction is a chemical synapse formed by the contact between a motor neuron and a muscle fiber, allowing the transmission of nerve impulses to cause muscle contraction

    .

    SECTION-B

    Answer any five of the following questions (All solved for full coverage):

    16. Describe the fluid-mosaic model of plasma membrane with a suitable diagram. Add a note on its functions. [8+2=10]

    The fluid-mosaic model, proposed by Singer and Nicolson, describes the plasma membrane as a fluid lipid bilayer with embedded "mosaic" proteins

    .
  • Lipid Bilayer: Composed of phospholipids with hydrophilic heads facing outward and hydrophobic tails facing inward.
  • Proteins: Integral proteins span the membrane, while peripheral proteins are attached to the surface.
  • Cholesterol: Regulates membrane fluidity.
  • Functions: Acts as a selective barrier, facilitates cell signaling, and provides structural support.

    17. Discuss the structure and functions of tight junctions and gap junctions. [5+5=10]

    Tight Junctions: Specialized connections where the membranes of adjacent cells are pressed tightly against each other, sealed by specific proteins (claudins and occludins)

    . They prevent the leakage of extracellular fluid.

    Gap Junctions: Channels (connexons) that connect the cytoplasm of adjacent cells, allowing the passage of ions and small molecules

    . They facilitate rapid chemical and electrical communication between cells, such as in cardiac muscle.

    18. Describe the structure and functions of endoplasmic reticulum (ER). [6+4=10]

    The ER is a network of membranous tubules and sacs called cisternae

    .
  • Rough ER (RER): Studded with ribosomes; functions in protein synthesis and modification.
  • Smooth ER (SER): Lacks ribosomes; functions in lipid synthesis, detoxification, and calcium storage.
  • 19. Describe the structure and functions of nucleus. Add a note on the functions of nucleolus. [8+2=10]

    The nucleus is the control center of the cell, enclosed by a double-membrane nuclear envelope containing nuclear pores

    . It contains nucleoplasm and chromatin (genetic material).

    Functions: Stores genetic information, controls gene expression, and regulates cell division

    .

    Functions of Nucleolus: The nucleolus is the site of ribosomal RNA (rRNA) synthesis and the assembly of ribosomal subunits

    .

    20. What is cytoskeleton? Describe the structure of a microfilament with suitable diagram and mention its functions. [2+6+2=10]

    Cytoskeleton: A network of protein fibers (microtubules, microfilaments, and intermediate filaments) that provides structural support and facilitates cell motility

    .

    Microfilament Structure: Composed of two intertwined strands of the protein actin

    .

    Functions: Maintaining cell shape, muscle contraction (with myosin), and amoeboid movement

    .

    21. Explain the key events that occur in each phase of cell cycle. Add a note on G1 checkpoint. [7+3=10]

  • Interphase: Includes G1 (cell growth), S (DNA replication), and G2 (preparation for mitosis).
  • M Phase (Mitosis): Division of the nucleus (Prophase, Metaphase, Anaphase, Telophase).
  • Cytokinesis: Division of the cytoplasm.
  • G1 Checkpoint: The primary point at which the cell must choose whether or not to divide

    . It checks for cell size, nutrients, growth factors, and DNA damage.

    22. What is epithelial tissue? Explain the structure with diagram and functions of simple epithelial tissue. [2+8=10]

    Epithelial Tissue: A tissue composed of closely packed cells that covers body surfaces and lines internal organs

    .

    Simple Epithelial Tissue: Consists of a single layer of cells

    . Types include:
  • Simple Squamous: Flat cells; functions in diffusion.
  • Simple Cuboidal: Cube-shaped; functions in secretion and absorption.
  • Simple Columnar: Tall cells; found in digestive tract.
  • 23. What are adipocytes? Describe the structure of three main types of cartilage. Add a note on the functions of cartilage. [2+6+2=10]

    Adipocytes: Specialized fat cells that store energy as lipids

    .

    Three Types of Cartilage:

  • Hyaline Cartilage: Most common; has clear matrix; found in joints.
  • Elastic Cartilage: Contains elastic fibers; found in external ear.
  • Fibrocartilage: Contains thick collagen fibers; provides high strength; found in intervertebral discs.
  • Functions: Provides structural support, cushions joints, and acts as a precursor for bone formation

    .

    24. Describe the structure and functions of a myelinated neuron. Add a note on different types of neuron based on polarity. [7+3=10]

    A myelinated neuron consists of a cell body, dendrites, and an axon covered by a fatty myelin sheath produced by Schwann cells

    . The gaps in the sheath are called Nodes of Ranvier.

    Functions: Saltatory conduction of nerve impulses (increases speed)

    .

    Types based on Polarity: Unipolar (one process), Bipolar (two processes), and Multipolar (multiple processes)

    .

    25. What is synapse? Differentiate between chemical synapse and electrical synapse. Describe the structure of different chemical synapses. [2+2+6=10]

    Synapse: A junction between two neurons where information is transmitted

    .

    Differences:

  • Chemical Synapse: Uses neurotransmitters; slower; unidirectional.
  • Electrical Synapse: Uses gap junctions; faster; often bidirectional.
  • Chemical Synapse Structure: Consists of a presynaptic terminal (containing vesicles), a synaptic cleft, and a postsynaptic membrane (containing receptors)

    .

    Exam Focus Enhancements

    Important Summary

  • Cell Theory: All living things are made of cells.
  • Mitochondria: Powerhouse (ATP).
  • Nucleus: Genetic control center.
  • Cartilage Types: Hyaline, Elastic, Fibrocartilage.
  • Exam Tips

    • Always label diagrams clearly (e.g., Plasma Membrane, Nucleus).
    • For 10-mark questions, use headings and bullet points for readability.
    • Distinguish clearly between "Tendon" and "Ligament" as they are common confusion points.
    Prokaryotic Cell Eukaryotic Cell
    Lacks a membrane-bound nucleus. Has a true membrane-bound nucleus. Membrane-bound organelles are absent. Membrane-bound organelles (e.g., mitochondria) are present.

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