Knowlet

UNIT 4: Sex Determination and Sex Linkage

Exam Focus: Differentiate between chromosomal and environmental sex determination. Understand the mechanism of X-inactivation/Dosage Compensation (Barr Bodies). Be prepared to solve simple problems involving X-linked recessive inheritance like Colour Blindness or Haemophilia.

Table of Contents

  1. Sex Determination
  2. Sex-linked Inheritance

1. Sex Determination

Sex determination is the biological system that determines the development of sexual characteristics in an organism.

Mechanisms of Sex Determination (Chromosomal)

The sex chromosomes (X and Y in humans) carry the genes that determine the sex.

Type Organism/Description Female Male
XX-XY Type Humans, Mammals, Drosophila (though determined differently) Homogametic (XX) Heterogametic (XY)
ZZ-ZW Type Birds, Reptiles, some Fishes Heterogametic (ZW) Homogametic (ZZ)
XX-X0 Type Grasshoppers, Cockroaches XX X0 (one X chromosome)

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