FYUG EVEN SEMESTER EXAM, 2024 ZOOLOGY (2nd Semester) Cell Biology and Histology

Course No.: ZOODSM-151T | Full Marks: 70 | Time: 3 Hours

Subject: Zoology (Cell Biology and Histology)

Paper Code: ZOODSM-151T

Exam: FYUG Even Semester Exam, 2024


SECTION-A

Answer any ten of the following questions (All solved for full coverage):

1. Define cell in the light of cell theory. [2]

According to cell theory, a cell is the basic structural, functional, and biological unit of all living organisms. It is the smallest unit of life that can replicate independently.

2. What do you mean by facilitated transport? [2]

Facilitated transport is a type of passive transport where molecules move across the cell membrane through specific transmembrane integral proteins without the expenditure of cellular energy.

3. Differentiate between prokaryotic and eukaryotic cell. [2]

Prokaryotic Cell Eukaryotic Cell
Lacks a membrane-bound nucleus. Has a true membrane-bound nucleus.
Membrane-bound organelles are absent. Membrane-bound organelles (e.g., mitochondria) are present.

4. Mention the functions of lysosome. [2]

  • Intracellular digestion of macromolecules.
  • Autophagy (digestion of old or damaged organelles).
  • Autolysis (self-destruction of the cell).

5. Mention important functions of peroxisome. [2]

  • Breakdown of fatty acids through beta-oxidation.
  • Detoxification of harmful substances (like alcohol) in the liver.
  • Conversion of hydrogen peroxide to water and oxygen by catalase.

6. Why is mitochondria called powerhouse of the cell? [2]

Mitochondria are called the powerhouse of the cell because they are the primary sites of ATP (Adenosine Triphosphate) production through cellular respiration.

7. What are microtubules? [2]

Microtubules are hollow, microscopic cylinders made of tubulin protein that form part of the cytoskeleton and play key roles in maintaining cell shape and facilitating cell division.

8. What are nucleosomes? [2]

A nucleosome is the basic structural unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound around a core of eight histone proteins.

9. Define cell cycle. [2]

The cell cycle is an ordered series of events involving cell growth and DNA replication that produces two new daughter cells.

10. What is pseudostratified epithelial tissue? [2]

It is a type of simple epithelium that appears layered (stratified) because the nuclei are at different levels, even though every cell is attached to the basement membrane.

11. Differentiate between tendon and ligament. [2]

  • Tendon: Connects skeletal muscle to bone.
  • Ligament: Connects bone to bone.

12. What is Haversian system? [2]

The Haversian system (or osteon) is the fundamental functional unit of compact bone, consisting of concentric layers of bone tissue surrounding a central canal containing blood vessels and nerves.

13. Enlist the locations of smooth muscle in human body. [2]

  • Walls of hollow organs (stomach, intestines).
  • Walls of blood vessels.
  • Urinary bladder and respiratory tracts.

14. What are glial cells? [2]

Glial cells (neuroglia) are non-neuronal cells in the nervous system that provide support, nutrition, and protection for neurons.

15. What is neuromuscular junction? [2]

A neuromuscular junction is a chemical synapse formed by the contact between a motor neuron and a muscle fiber, allowing the transmission of nerve impulses to cause muscle contraction.


SECTION-B

Answer any five of the following questions (All solved for full coverage):

16. Describe the fluid-mosaic model of plasma membrane with a suitable diagram. Add a note on its functions. [8+2=10]

The fluid-mosaic model, proposed by Singer and Nicolson, describes the plasma membrane as a fluid lipid bilayer with embedded "mosaic" proteins.

  • Lipid Bilayer: Composed of phospholipids with hydrophilic heads facing outward and hydrophobic tails facing inward.
  • Proteins: Integral proteins span the membrane, while peripheral proteins are attached to the surface.
  • Cholesterol: Regulates membrane fluidity.
Functions: Acts as a selective barrier, facilitates cell signaling, and provides structural support.

17. Discuss the structure and functions of tight junctions and gap junctions. [5+5=10]

Tight Junctions: Specialized connections where the membranes of adjacent cells are pressed tightly against each other, sealed by specific proteins (claudins and occludins). They prevent the leakage of extracellular fluid.

Gap Junctions: Channels (connexons) that connect the cytoplasm of adjacent cells, allowing the passage of ions and small molecules. They facilitate rapid chemical and electrical communication between cells, such as in cardiac muscle.

18. Describe the structure and functions of endoplasmic reticulum (ER). [6+4=10]

The ER is a network of membranous tubules and sacs called cisternae.

  • Rough ER (RER): Studded with ribosomes; functions in protein synthesis and modification.
  • Smooth ER (SER): Lacks ribosomes; functions in lipid synthesis, detoxification, and calcium storage.

19. Describe the structure and functions of nucleus. Add a note on the functions of nucleolus. [8+2=10]

The nucleus is the control center of the cell, enclosed by a double-membrane nuclear envelope containing nuclear pores. It contains nucleoplasm and chromatin (genetic material).

Functions: Stores genetic information, controls gene expression, and regulates cell division.

Functions of Nucleolus: The nucleolus is the site of ribosomal RNA (rRNA) synthesis and the assembly of ribosomal subunits.

20. What is cytoskeleton? Describe the structure of a microfilament with suitable diagram and mention its functions. [2+6+2=10]

Cytoskeleton: A network of protein fibers (microtubules, microfilaments, and intermediate filaments) that provides structural support and facilitates cell motility.

Microfilament Structure: Composed of two intertwined strands of the protein actin.

Functions: Maintaining cell shape, muscle contraction (with myosin), and amoeboid movement.

21. Explain the key events that occur in each phase of cell cycle. Add a note on G1 checkpoint. [7+3=10]

  • Interphase: Includes G1 (cell growth), S (DNA replication), and G2 (preparation for mitosis).
  • M Phase (Mitosis): Division of the nucleus (Prophase, Metaphase, Anaphase, Telophase).
  • Cytokinesis: Division of the cytoplasm.

G1 Checkpoint: The primary point at which the cell must choose whether or not to divide. It checks for cell size, nutrients, growth factors, and DNA damage.

22. What is epithelial tissue? Explain the structure with diagram and functions of simple epithelial tissue. [2+8=10]

Epithelial Tissue: A tissue composed of closely packed cells that covers body surfaces and lines internal organs.

Simple Epithelial Tissue: Consists of a single layer of cells. Types include:

  • Simple Squamous: Flat cells; functions in diffusion.
  • Simple Cuboidal: Cube-shaped; functions in secretion and absorption.
  • Simple Columnar: Tall cells; found in digestive tract.

23. What are adipocytes? Describe the structure of three main types of cartilage. Add a note on the functions of cartilage. [2+6+2=10]

Adipocytes: Specialized fat cells that store energy as lipids.

Three Types of Cartilage:

  1. Hyaline Cartilage: Most common; has clear matrix; found in joints.
  2. Elastic Cartilage: Contains elastic fibers; found in external ear.
  3. Fibrocartilage: Contains thick collagen fibers; provides high strength; found in intervertebral discs.

Functions: Provides structural support, cushions joints, and acts as a precursor for bone formation.

24. Describe the structure and functions of a myelinated neuron. Add a note on different types of neuron based on polarity. [7+3=10]

A myelinated neuron consists of a cell body, dendrites, and an axon covered by a fatty myelin sheath produced by Schwann cells. The gaps in the sheath are called Nodes of Ranvier.

Functions: Saltatory conduction of nerve impulses (increases speed).

Types based on Polarity: Unipolar (one process), Bipolar (two processes), and Multipolar (multiple processes).

25. What is synapse? Differentiate between chemical synapse and electrical synapse. Describe the structure of different chemical synapses. [2+2+6=10]

Synapse: A junction between two neurons where information is transmitted.

Differences:

  • Chemical Synapse: Uses neurotransmitters; slower; unidirectional.
  • Electrical Synapse: Uses gap junctions; faster; often bidirectional.

Chemical Synapse Structure: Consists of a presynaptic terminal (containing vesicles), a synaptic cleft, and a postsynaptic membrane (containing receptors).